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Figure 1. Comparison of pulmonary sarcoidosis granuloma
histology to other granulomatous lung diseases
A) Typical sarcoidosis histology with well-formed granulomas comprised
of macrophage aggregates (G) and featuring multinucleated giant
cells (white arrows, inset), with minimal surrounding lymphocytic
inflammation (L).
B) Hypersensitivity pneumonitis featuring smaller granulomas (G) with
more extensive surrounding lymphocytic alveolitis (L).
C) A large acellular necrotizing granuloma (NG) caused by pulmonary
Histoplasma capsulatum infection.
A B
C
