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Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. e guideline provides evidence-based recommendations that have been developed using GR ADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodolog y. GR ADE involves structured literature review, systematic reviews and meta-analyses of combined data, and expert discussion to assess the certainty in the evidence and determine the strength of each recommendation. Source Crouser, E, Maier, L, Wilson, K, Bonham, ., Morgenthau, A, & Patterson, K. et al. (2020). Diagnosis and Detection of Sarcoidosis. An Official American oracic Society Clinical Practice Guideline. Am J Respir Crit Care Med, 201(8), e26-e51. doi: 10.1164/ rccm.202002-0251st 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at Copyright © 2020 All rights reserved ATSSAR07202a Abbreviations ACE, angiotensin-converting enzyme; Ag, antigen; ANCA, antineutrophil cytoplasmic antibody; AV, atrioventricular; AVNB, atrioventricular node block; CCP, cyclic citrullinated peptide; CM, cardiomyopathy; CNS, central nervous system; CT, computed tomography; CVID, common variable immune deficiency; CXR, chest X-ray; EBV, Epstein-Barr virus; EGPA, eosinophilic GPA; EIA, enzyme-linked immunoassays; GI, gastrointestinal; GLIL, granulomatous–lymphocytic interstitial lung disease; GLUS, granulomatous lesions of unknown significance syndrome; GPA, granulomatosis with polyangiitis; LIP, lymphocytic interstitial pneumonia; LVEF, le ventricular ejection fraction; M. kansasii, Mycobacterium kansasii; MAC, Mycobacterium avium complex; MPA, microscopic polyangiitis; MPO, myeloperoxidase; MRI, magnetic resonance imaging ; NK, natural killer; NSAIDs, nonsteroidal antiinflammatory drugs; p-ANCA, perinuclear ANCA; PET, positron emission tomography; PICO, problem, intervention, comparison, outcome question format; PR3, PR3-ANCA; TNF, tumor necrosis factor. VT, ventricular tachycardia

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