ASAM Pocket Guidelines and Patient Guide

Alcohol Withdrawal Management

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35 (2) AUD treatment initiation and engagement Î Recommendation VII.30: Engagement in treatment for AUD is particularly important for pregnant patients with alcohol withdrawal given the risk of Spectrum Disorder (FASD) including Fetal Alcohol Syndrome (FAS). (3) Pharmacotherapy Î Recommendation VII.31: Before giving any medications to pregnant patients, ensure that patients understand the risks and benefits of the medication, both for the patient and the developing fetus. Î Recommendation VII.32: Benzodiazepines and barbiturates are the medications of choice in treatment of pregnant patients with alcohol withdrawal. While there is a risk of teratogenicity during the first trimester, the risks appear small, and they are balanced in view of the risk for fetal alcohol spectrum disorder and consequences to mother and fetus should severe maternal alcohol withdrawal develop. Î Recommendation VII.33: Due to the high teratogenic risk, valproic acid is not recommended for pregnant patients. Î Recommendation VII.34: For patients at risk for pre-term delivery or in the late third trimester, use of a short-acting benzodiazepine is recommended. This minimizes the risk for neonatal benzodiazepine intoxication given shorter onset and duration of action. (4) Newborn considerations Î Recommendation VII.35: In cases of alcohol withdrawal treated close to delivery, assess the newborn for benzodiazepine intoxication, sedative withdrawal, and Spectrum Disorder (FASD) including Fetal Alcohol Syndrome (FAS). Î Recommendation VII.36: Inform pregnant patients of all wraparound services that will assist them in addressing newborn needs, including food, shelter, pediatric clinics for inoculations, as well as programs that will help with developmental or physical issues that the newborn may experience as a result of in-utero substance exposure. Î Recommendation VII.37: Licensed clinical staff have an obligation to understand and follow their state laws regarding definitions of child abuse and neglect, reporting requirements, and plans for safe care of newborns with in-utero alcohol exposure.

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