11
Level 2-WM
Appropriate Neutral/Uncertain Inappropriate
Mild or moderate (e.g.,
CIWA-Ar <0–18).
Severe but not complicated
(e.g., CIWA-Ar ≥19).
Complicated (e.g., CIWA-
Ar ≥19).
Physiological dependence
on opioids or OUD.
Withdrawing from other
substance(s).
Physiological dependence
on BZDs or BZD use
disorder.
Severe withdrawal >1 year
ago.
Previous complicated
withdrawal episode.
Recent severe withdrawal
episode.
Previous failure to benefit
from Amb-WM.
Medical or psychiatric
condition that needs
inpatient treatment.
Older age.
History of epilepsy.
Moderate, active, and
potentially destabilizing
medical problem.
History of non-alcohol
related seizure.
Clinically significant
abnormal lab results.
Suspected head injury.
Moderate to severe
active and potentially
destabilizing medical
problem including
unstable chronic
condition.
Unable to take oral
medications.
