Disclaimer
is pocket guide attempts to define principles of practice that should produce high-quality
patient care. It is applicable to specialists, primary care, and providers at all levels. is
pocket guide should not be considered exclusive of other methods of care reasonably directed at
obtaining the same results. e ultimate judgment concerning the propriety of any course of
conduct must be made by the clinician aer consideration of each individual patient situation.
Neither IGC, the medical associations, nor the authors endorse any product or service associated
with the distributor of this clinical reference tool.
e guideline provides evidence-based recommendations that have been developed
using GR ADE (Grading of Recommendations, Assessment, Development, and
Evaluation) methodolog y. GR ADE involves structured literature review, systematic
reviews and meta-analyses of combined data, and expert discussion to assess the
certainty in the evidence and determine the strength of each recommendation.
Source
Nahid P, Mase S, Battista G, et al. Treatment of Drug-Resistant Tuberculosis
Am J Respir Crit Care Med. 2019;200(10):pp e93–e142.
e guideline was a cooperative effort among the American oracic Society, the United
States Centers for Disease Control and Prevention, the European Respiratory Society, and
the Infectious Diseases Society of America.
106 Commerce Street, Suite 105
Lake Mary, FL 32746
TEL: 407.878.7606 • FAX: 407.878.7611
Order additional copies at GuidelineCentral.com
Copyright © 2020 All rights reserved
ATSMDRTB01202a
Abbreviations
ATS, American oracic Society; CDC, Center for Disease Control and Prevention;
DR-TB, drug-resistant TB; DST, drug susceptibility test; ERS, European Respiratory
Society; IDSA, Infectious Diseases Society of America; IM, intramuscular; IPDMA,
Individual Patient/Participant Data Meta-Analysis; IV, intravenous; MDR-TB, multiple
drug-resistant TB; PO, oral; pre-XDR-TB, pre-extensively drug-resistant TB; TDM,
erapeutic Drug Monitoring ; TB, tuberculosis; XDR-TB, extensively drug-resistant TB;
WHO, World Health Organization
