9
≤10% of cells
staining OR
intensity is weak
Step 2: Evaluate percent of cancer cells staining and stain intensity
>10% of cells staining
AND intensity is
moderate or strong
Take steps to confirm/
adjudicate result per
labspecific SOP
a
and
correlate with histology
(See Table 1)
Report as:
ER Positive
If result considered concordant with
histology (See Table 1)
<1% of cells
staining
1-100% of cells
staining
Report as: ER
Negative
(reported data
elements should
include status of
controls
c
)
ER Positive
1-10% of cells
staining
>10% of cells
staining (but weak)
Report as: ER Low Positive
Add recommended comment
b
(reported data elements should
include percentage of cells
staining, intensity, and status of
controls
c
)
Report as: ER Positive
(reported data elements
should include
percentage of cells
staining and intensity)
