11
Prior Respiratory
Isolation of
P. aeruginosa
Recent Hospitalization
and Parenteral
Antibiotics and Locally
Validated Risk Factors
for MRSA
Recent Hospitalization
and Parenteral
Antibiotics and Locally
Validated Risk Factors
for P. aeruginosa
Add coverage for P.
aeruginosa
e
and obtain
cultures to allow de-
escalation or confirmation
of need for continued
therapy
Obtain cultures but
withhold MRSA coverage
unless culture results are
positive. If rapid nasal
PCR is available, withhold
additional empiric therapy
against MRSA if rapid
testing is negative or add
coverage if PCR is positive
and obtain cultures
Obtain cultures but initiate
coverage for P. aeruginosa
coverage only if culture
results are positive
Add coverage for P.
aeruginosa
e
and obtain
cultures to allow de-
escalation or confirmation
of need for continued
therapy
Add MRSA coverage
d
and obtain nasal PCR
and cultures to allow de-
escalation or confirmation
of need for continued
therapy
Add coverage for P.
aeruginosa
e
and obtain
cultures to allow de-
escalation or confirmation
of need for continued
therapy
