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106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved ESHIR1852a Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation.Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Source Martin KA, Anderson RR, Chang RJ, Ehrmann DA, Lobo RA, Murad MH, Pugeat MM, Rosenfield RL. Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab, 2018 Mar 7. doi: 10.1210/jc.2018- 00241. [Epub ahead of print] Abbreviations CPA, cyproterone acetate; DSP, drospirenone; EE, ethinyl estradiol; GnRH, gonadotropin- releasing hormone; IPL, intense pulsed light; NCCAH, nonclassical congenital adrenal hyperplasia; OC, oral contraceptive; PCOS, polycystic ovary syndrome; PH, paradoxical hypertrichosis; SHBG, sex hormone-binding globulin; VTE, venous thromboembolism Grading System Strength of Recommendation 1 = strong 2 = conditional UGPS = ungraded good practice statement Quality of Evidence ⊕⊕⊕⊕ = high ⊕⊕⊕ = moderate ⊕⊕ = low ⊕ = very low

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