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Disclaimer
is pocket guide is derived om recommendations in the American Society of Clinical Oncology Guideline. is
resource is a practice tool based on ASCO
®
practice guidelines and is not intended to substitute for the independent
professional judgment of the treating physician. Practice guidelines do not account for individual variation among
patients. is pocket guide does not purport to suggest any particular course of medical treatment. Use of the practice
guidelines and this resource are voluntary. e practice guidelines and additional information are available at www.
asco.org/breast-cancer-guideline. Copyright © 2019 by American Society of Clinical Oncology. All rights reserved.
ASCOBIO1953
ASCO believes that cancer clinical trials are vital to inform medical decisions and
improve cancer care and that all patients should have the opportunity to participate.
Additional information, which may include data supplements, slide sets,
patient versions, and other clinical tools and resources, is available at
www.asco.org/breast-cancer-guidelines
Recommendation Grading
Type Evidence Quality
Strength of
Recommendation
EB Evidence-based H High Strong
IC Informal consensus I Intermediate Moderate
L Low Weak
Ins Insufficient
The distribution of this educational resource was supported by
Genomic Health, Inc.
Source
Andre F et al. Use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage
invasive breast cancer: American Society of Clinical Oncolog y Clinical Practice Guideline Update. J Clin
Oncol. 2019 May 31; doi: 10.1200/JCO.19.00945.
Krop I et al. Use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage
invasive breast cancer: Focused Update of 2016 American Society of Clinical Oncolog y Clinical Practice
Guideline. J Clin Oncol. 2017 Aug 20;35(24):2838-2847.
Harris LN et al. Use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage
invasive breast cancer: American Society of Clinical Oncolog y Clinical Practice Guideline. J Clin Oncol. 2016
Apr 1;34(10):1134-50.
