5
Table 3. High-Resolution CT Scanning Patterns
UIP Probable UIP
Indeterminate
for UIP Alternative Diagnosis
Subpleural and
basal
predominant;
distribution
is oen
heterogeneous
a
Honeycombing
with or without
peripheral
traction
bronchiectasis or
bronchiolectasis
b
Subpleural
and basal
predominant;
distribution
is oen
heterogeneous
Reticular
pattern with
peripheral
traction
bronchiectasis
or
bronchiolectasis
May have mild
GGO
Subpleural
and basal
predominant
Subtle
reticulation;
may have
mild GGO
or distortion
("early UIP
pattern")
CT features
and/or
distribution of
lung fibrosis
that do not
suggest any
specific
etiolog y ("truly
indeterminate")
Findings suggestive of another
diagnosis, including :
• CT features:
▶ Cysts
▶ Marked mosaic
attenuation
▶ Predominant GGO
▶ Profuse micronodules
▶ Centrilobular nodules
▶ Nodules
▶ Consolidation
• Predominant distribution:
▶ Peribronchovascular
▶ Perilymphatic
▶ Upper or mid-lung
• Other:
▶ Pleural plaques (consider
asbestosis)
▶ Dilated esophagus
(consider CTD)
▶ Distal clavicular erosions
(consider RA)
▶ Extensive lymph node
enlargement (consider
other etiologies)
▶ Pleural effusions, pleural
thickening (consider
CTD/drugs)
a
Variants of distribution: occasionally diffuse, may be asymmetrical.
b
Superimposed CT features: mild GGO, reticular pattern, pulmonary ossification.
