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ST-Elevation Myocardial Infarction

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Complications After STEMI Cardiogenic Shock ÎÎEmergency revascularization with either PCI or CABG is recommended in suitable patients with cardiogenic shock due to pump failure after STEMI irrespective of the time delay from MI onset. (I-B) ÎÎIn the absence of contraindications, fibrinolytic therapy should be administered to patients with STEMI and cardiogenic shock who are unsuitable candidates for either PCI or CABG. (I-B) ÎÎThe use of intra-aortic balloon pump (IABP) counterpulsation can be useful for patients with cardiogenic shock after STEMI who do not quickly stabilize with pharmacological therapy. (IIa-B) ÎÎAlternative LV assist devices for circulatory support may be considered in patients with refractory cardiogenic shock. (IIb-C) Implantable Cardioverter-Defibrillator Therapy Before Discharge ÎÎImplantable cardioverter-defibrillator (ICD) therapy is indicated before discharge in patients who develop sustained VT/VF more than 48 hours after STEMI, provided the arrhythmia is not due to transient or reversible ischemia, reinfarction, or metabolic abnormalities. (I-B) Bradycardia, AV Block, and Intraventricular Conduction Defects Pacing in STEMI ÎÎTemporary pacing is indicated for symptomatic bradyarrhythmias unresponsive to medical treatment. (I-C) Pericarditis ÎÎAspirin is recommended for treatment of pericarditis after STEMI. (I-B) ÎAdministration of acetaminophen, colchicine, or narcotic analgesics may Î be reasonable if aspirin, even in higher doses, is not effective. (IIb-C) ÎGlucocorticoids and nonsteroidal anti-inflammatory drugs are potentially Î harmful for treatment of pericarditis after STEMI. (III-B: Harm) Table 13. Selected Risk Factors for Bleeding in Patients With ACS Advanced age (>75 y) Presentation with STEMI or NSTEMI (vs. UA) Female sex Severe renal dysfunction (CrCl <30 mL/min) HF or shock Elevated white blood cell count Diabetes Use of fibrinolytic therapy Body size Invasive strategy History of GI bleeding Inappropriate dosing of antithrombotic medications Anemia 23

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