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Stable Ischemic Heart Disease

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Treatment 28 Medical Therapy for Relief of Symptoms Use Of Antiischemic Medications Î Beta blockers should be prescribed as initial therapy for relief of symptoms in patients with SIHD. (I-B) Î Calcium channel blockers or long-acting nitrates should be prescribed for relief of symptoms when beta blockers are contraindicated or cause unacceptable side effects in patients with SIHD. (I-B) Î Calcium channel blockers or long-acting nitrates, in combination with beta blockers, should be prescribed for relief of symptoms when initial treatment with beta blockers is unsuccessful in patients with SIHD. (I-B) Î Sublingual nitroglycerin or nitroglycerin spray is recommended for immediate relief of angina in patients with SIHD. (I-B) ÎTreatment with a long-acting nondihydropyridine calcium channel blocker (verapamil or diltiazem) instead of a beta blocker as initial therapy for relief of symptoms is reasonable in patients with SIHD. (IIa-B) Î Ranolazine can be useful when prescribed as a substitute for beta blockers for relief of symptoms in patients with SIHD if initial treatment with beta blockers leads to unacceptable side effects or is ineffective or if initial treatment with beta blockers is contraindicated. (IIa-B) Î Ranolazine in combination with beta blockers can be useful when prescribed for relief of symptoms when initial treatment with beta blockers is not successful in patients with SIHD. (IIa-A)

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