Selecting a Treatment Regimen
Table 1. Antifungal Therapy for IA
Antifungal (Brand)
Dosage Form*
AMB Formulations
D-AMB
IV
Lipid Formulations of AMB (LFABs)
ABCD (Amphocil ®, Amphotec ®)
IV
®
ABLC (Abelcet )
IV
L-AMB (AmBisome ®)
IV
Triazoles
Voriconazole (VFEND ®)
IV or PO
(tablets, oral suspension)
Itraconazole (Sporanox ®)
IV or PO
(capsules, oral solution)
Posaconazole (Noxafil ®†)
PO
(oral suspension)
Echinocandins
Caspofungin (Cancidas ®)
IV
Micafungin (Mycamine ®)
IV
Anidulafungin (ERAXIS ®)
IV
AMB, amphotericin B; D-AMB, AMB deoxycholate; ABLC, AMB lipid complex; L-AMB, liposomal AMB; HSC
* Dosage varies with type and location of IA (see Table 2).
†
http://www.centerwatch.com/patient/drugs/dru908.html; accessed May 7, 2009.
