Diagnosis and Assessment of Disease
Management of Vaccine Reactions (continued)
Are nature and timing of reaction consistent with anaphylaxis? (Note 1)
or
Is there a history of possible anaphylaxis to previous doses of this or other
vaccines or foods, specifically gelatin, egg, chicken or yeast?
YES
NO
Administer vaccine unless reaction
is a contraindication,
eg, encephalopathy after pertussis
vaccine
Skin test with vaccine and
components (Note 2)
+
Additional doses
needed? (Note 3)
– give graded doses
and prepare to treat
anaphylaxis (Note 4)
2
–
Additional doses
needed? (Note 3) – give
full vaccine and observe
for ≥ 30 mins
