AASLD GUIDELINES Bundle (free trial)

Hepatitis B

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Recommendation Grading Grade Definition I Randomized controlled trials II-1 Controlled trials without randomization II-2 Cohort or case-control analytic studies II-3 Multiple time series, dramatic uncontrolled experiments III Opinions of respected authorities, descriptive epidemiology Abbreviations ADV, adefovir; AFP, alpha fetoprotein; ALT, alanine aminotransferase; anti-HBc, hepatitis B core antibody; anti-HBe, antibody to hepatitis B e antigen; anti-HBs, hepatitis B surface antibody; AST, aspartate aminotransferase; ClCr, creatinine clearance; ETV, entecavir; HAART, highly active antiretroviral therapy; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HDV, hepatitis D virus; HIV, human immunodeficiency virus; IFN-��, interferon-alpha; IU, international unit; LAM, lamivudine; LdT, telbivudine; MU, million units; NA, nucleoside analogues; PCR, polymerase chain reaction; pegIFN-��, pegylated interferon-alpha; q, every; qd, daily; TDF, tenofovir disoproxil fumarate; ULN, upper limit of normal Source Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology. 2009;50(3):661-662. Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. HEB10122a 5740 Executive Drive��� Suite 218 Baltimore, MD 21228��� TEL: 410-869-3332��� ������ FAX: 410-744-2150��� For additional copies: orders@GuidelineCentral.com Copyright �� 2012 All rights reserved

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