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Neck Mass in Adults

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2 Key Points Table 1. Summary of Guideline Key Action Statements (KAS) Statement Action Strength 1. Avoidance of antibiotic therapy Clinicians should NOT routinely prescribe antibiotic therapy for patients with a neck mass unless there are signs and symptoms of bacterial infection. R 2a. Standalone suspicious history Clinicians should identify patients with a neck mass who are at increased risk for malignancy because the patient lacks a history of infectious etiolog y and the mass has been present for 2 weeks or longer without significant fluctuation, or the mass is of uncertain duration. R 2b. Standalone suspicious physical examination Clinicians should identify patients with a neck mass who are at increased risk for malignancy based on one or more of these physical examination characteristics: fixation to adjacent tissues, firm consistency, size greater than 1.5 cm, and/or ulceration of overlying skin. R 2c. Additional suspicious signs and symptoms Clinicians should conduct an initial history and physical examination for adults with a neck mass to identify those patients with other suspicious findings that represent an increased risk for malignancy. R 3. Follow up of the patient not at increased risk For patients with a neck mass who are not at increased risk for malignancy, clinicians or their designees should advise patients of criteria that would trigger the need for additional evaluation. Clinicians or their designees should also document a plan for follow up to assess resolution or final diagnosis. R 4. Patient education For patients with a neck mass who are deemed at increased risk for malignancy, clinicians or their designees should explain to the patient the significance of being at increased risk, and explain any recommended diagnostic tests. R 5. Targeted physical examination Clinicians should perform, or refer the patient to a clinician who can perform, a targeted physical examination (including visualizing the mucosa of the larynx, base of tongue, and pharynx) for patients with a neck mass deemed at increased risk for malignancy. R 6. Imaging Clinicians should order a neck CT (or MRI) with contrast for patients with a neck mass deemed at increased risk for malignancy. S

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