Prevention
In Maximal And Enhanced Resource Settings
Recommendation A1a
➤ Public health authorities, ministries of health, and primary care providers
should routinely vaccinate girls with the target age range being as
early as possible starting at 9 years through 14 years of age (Strong
Recommendation; EB-H).
Recommendation A1b
➤ Public health authorities may set the upper end of the target population
higher than 14 years of age, depending on local policies and resources
(Moderate Recommendation; EB-L).
Recommendation A2a
➤ For girls 9–14 years of age who are immune competent, a two-dose
regimen is recommended (Moderate Recommendation; EB-I).
Recommendation A2b
➤ The interval between two doses should be at least 6 months and may be
up to 12–15 months (6 months: Strong Recommendation; EB-H, 12–15
months: Weak Recommendation; EB-L).
Recommendation A2c
➤ Girls ≥15 years of age at the time of the first dose/initiation (outside
of target population) who receive vaccine should receive three doses
(Moderate Recommendation; IC-I).
Recommendation A3
➤ For females who have received one dose and are >14 years of age, public
health authorities may provide additional doses/complete the series up to
26 years of age (Moderate Recommendation; EB-I).
Recommendation A4
a
➤ For prevention of cervical cancer, if there is low vaccine coverage of
the priority female target population (<50%) in maximal or enhanced
resource settings, then vaccination may be extended to boys (Moderate
Recommendation; EB-I).
• For prevention of cervical cancer in maximal or enhanced resource settings where
vaccine coverage of girls is ≥50%, then vaccination of boys is not recommended
(Weak Recommendation; EB-Ins).
