Key Points
Î Microscopic colitis is characterized by chronic watery diarrhea
caused by inflammation in the colon and diagnosed by colonic
biopsy.
Î The reported prevalence of microscopic colitis ranges from
48–219 per 100,000.
Î There is a predilection for those ≥60 years of age.
Î There are 2 subtypes: lymphocytic colitis and collagenous
colitis. There is a female predominance in the latter.
Î Microscopic colitis is not associated with increased mortality.
Î The goal of medical therapy reflected in these
recommendations is to relieve symptoms and improve quality
of life while minimizing drug-related adverse effects.
AGA Institute Guideline on the Medical Management of Microscopic Colitis