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Copyright © 2016 All rights reserved
Disclaimer
is pocket card is derived om recommendations in the American Society of Clinical Oncolog y
Guideline. is resource is a practice tool based on ASCO
®
practice guidelines and is not intended to
substitute for the independent professional judgment of the treating physician. Practice guidelines do
not account for individual variation among patients. is pocket card does not purport to suggest any
particular course of medical treatment. Use of the practice guidelines and this resource are voluntary.
e practice guidelines and additional information are available at www.asco.org/guidelines/
advancedendocrinebreast. Copyright © 2016 by American Society of Clinical Oncolog y.
All rights reserved.
ASCOHREN16113
Abbreviations
AI, aromatase inhibitor; ER, estrogen receptor; HER2, human epidermal growth factor
receptor 2; HER2+, human epidermal growth factor receptor 2-positive; HR+, hormone
receptor-positive; MBC, metastatic breast cancer; OS, ovarian function suppression; PFS,
progression-free survival; PR, progesterone receptor, qd, daily; tid, three times a day
Source
Rugo HS, Rumble RB, Macrae E, Barton DL, Connolly HK, Dickler MN, Fallowfield L, Fowble
B, Ingle JN, Jahanzeb M, Johnston SR, Korde LA, Khatcheressian JL, Mehta RS, Muss HB,
Burstein HJ. Endocrine erapy for Hormone Receptor-Positive Metastatic Breast Cancer:
American Society of Clinical Oncolog y Guideline. J Clin Oncol. 2016 Sep 1;34(25):3069-3103.
Recommendation Grading
Type Benefit/harm Evidence Quality
Strength Of
Recommendation
EB Evidence-based B Benefits
outweigh harms
H High S Strong
CB
Consensus-
based
H
Harms outweigh
benefits
I Intermediate M Moderate
L Low W Weak
ASCO believes that cancer clinical trials are vital to inform medical decisions and
improve cancer care and that all patients should have the opportunity to participate.
Additional information, which may include data supplements, slide sets, patient
versions, frequently asked questions, and other clinical tools and resources, is available at
www.asco.org/guidelines/advancedendocrinebreast and www.asco.org/guidelineswiki