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Rhinosinusitis

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Treatment Table 6. Available Antibacterials Generic Amoxicillin-clavulanate Cefixime Cefotaxime Cefpodoxime Ceſtriaxone Clindamycin Doxycycline Levofloxacin Moxifloxacin Available as Augmentin® Suprax® Claforan® Vantin® , generic , generic , generic , generic Rocephin® Cleocin® , generic , generic Vibramycin® Levaquin® Avelox® Bactrim® , generic , generic , Septra® , generic Table 7. Indications for Referral to a Specialist Severe infection (high persistent fever with temperature > 102ºF; orbital edema; severe headache, visual disturbance, altered mental status, meningeal signs) Recalcitrant infection with failure to respond to extended courses of antimicrobial therapy Immunocompromised host Multiple medical problems which might compromise response to treatment (eg, hepatic or renal impairment, hypersensitivity to antimicrobial agents, organ transplantation, etc.) Unusual or resistant pathogens Fungal sinusitis or granulomatous disease Nosocomial infection Anatomic defects causing obstruction and requiring surgical intervention Multiple recurrent episodes of ABRS (3-4 episodes per year) suggesting chronic sinusitis Chronic rhinosinusitis (with or without polyps or asthma) with recurrent ABRS exacerbations Evaluation of immunotherapy for allergic rhinitis

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