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Uncomplicated UTI

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Strength of Recommendation and Quality of Evidence Category/Grade Definition Strength of Recommendation A B C Quality of Evidence I II III Abbreviations bid, twice a day; C&S, culture and sensitivity; d, day; ER, extended release; IM, intramuscular; IV, intravenous; PO, orally; TMP-SMX DS, trimethoprim-sulfamethoxazole double strength (160/800 mg); UTI, urinary tract infection Source Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG, Moran GJ, Nicolle LE, Raz R, Schaeffer AJ, Soper DE. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: a 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011;52(5):e103-e120. Good evidence to support a recommendation for or against use. Moderate evidence to support a recommendation for or against use. Poor evidence to support a recommendation. Evidence from ≥ 1 properly randomized, controlled trial. Evidence from ≥ 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from > 1 center); from multiple time-series; or from dramatic results of uncontrolled experiments. Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees. Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. 5740 Executive Drive Suite 218 Baltimore, MD 21228 TEL: 410-869-3332 • FAX: 410-744-2150 For additional copies: orders@GuidelineCentral.com Copyright © 2012 All rights reserved UNC021214

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