Strength of Recommendation and Quality of Evidence Strength of Recommendation Quality of Evidence A Strong
I High: Further research is very unlikely to have an impact on the quality of the body of evidence, and therefore the confidence in the recommendation is high and unlikely to change.
B Weak
II Moderate: Further research is likely to have an impact on the quality of the body of evidence and may change the recommendation.
III Low: Further research is very likely to have an important impact on the body of evidence and is likely to change the recommendation.
Abbreviations AAP, American Academy of Pediatrics; ACD, allergic contact dermatitis; ACIP, Advisory Committee on Immunization Practices (CDC); AD, atopic dermatitis; AP, allergic proctocolitis; APT, atopy patch test; EoE, eosinophilic esophagitis; EG, eosinophilic gastroenteritis; EP, expert panel; FA, food allergy; FPIES, food protein-induced enterocolitis syndrome; GI, gastrointestinal; IM, intramuscular; IV, intravenous; LTR, life-threatening reaction; MDI, metered-dose inhaler; OAS, oral allergy syndrome; sIgE, allergen-specific IgE; SPT, skin puncture test
Source & Acknowledgements This Pocket Guide was based on recent guidelines developed with support of the National Institute of Allergy and Infectious Diseases (NIAID). NIAID staff worked with 34 professional organizations, federal agencies, and patient advocacy groups to develop concise clinical guidelines for healthcare professionals on the diagnosis and management of food allergy and the treatment of acute food allergy reactions. The recommendations made in these guidelines were developed by an 25-member independent expert panel using an comprehensive systematic literature review prepared by the RAND Corporation. These guidelines were published in 2010: Boyce JA, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010 Dec;126(6 Suppl): S1-S58. PMID: 21134576
Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.
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