IDSA/SHEA Clostridium difficile Infection - 2018 Update

5 Table 1. Summary of Available Tests for CDI in Decreasing Order of Sensitivity Test Sensitivity Specificity Substance Detected Toxigenic culture (TC) High Low a C. difficile vegetative cells or spores Nucleic acid amplification tests (NAAT) High Low/moderate C. difficile toxin genes Glutamate dehydrogenase (GDH) High Low a C. difficile common antigen Cell culture cytotoxicity neutralization assay (CCNA) High High Free toxins Toxin A, B enzyme immunoassays Low Moderate Free toxins a Must be combined with a toxin test.

• Cover
• Key Points & Epidemiology
• Diagnosis
• Infection Prevention & Control
• Treatment
• Grading Table
• Abbreviations and Source
• Drug Table
• Summary of CDI Tests