IDSA GUIDELINES Bundle (free trial)

Outpatient Community-Acquired Pneumonia

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Table 3. Recommended Antimicrobials for Outpatient Treatment of CAP (continued) Antimicrobial Miscellaneous Clindamycin (Cleocin® Doxycycline (Vibramycin® , others) , others) Route PO PO Adult Dose* 450 mg q6h OR 600 mg q8h 100 mg q12h Comments > Clindamycin active against S. pneumoniae but not active against H. influenzae or atypical pathogens > Doxycycline active against strains of S. pneumoniae, H. influenzae, and atypical pathogens; generally well tolerated * For normal renal function. † Dose recommended in IDSA/ATS GUIDELINES (2007). ‡ This dose for patients with normal renal function. • See product labeling for complete prescribing information. NOTE. Choices should be modified on the basis of susceptibility test results and advice from local specialists. Refer to local references for appropriate doses. Abbreviations ACIP, Advisory Committee on Immunization Practices; ATS, American Thoracic Society; bid, twice daily; BUN, blood urea nitrogen; C, celsius; CA-MRSA, community- acquired methicillin-resistant Staphylococcus aureus; CAP, community-acquired pneumonia; COPD, chronic obstructive pulmonary disease; CURB-65, confusion, urea nitrogen, respiratory rate, low blood pressure, age ≥ 65 years; d, day; dL, deciliter; ED, emergency department; h, hour(s); HCAP, health care asoociated pneumonia; Hg, mercury; ICU, intensive care unit; IDSA, Infectious Diseases Society of America; IM, intramuscular; IV, intravenous; MIC, minimum inhibitory concentration; mg, milligram; mL, milliliter; mm, millimeter; NA, not applicable; PaO2 fraction of inspired oxygen; PO, oral; PSI, pneumonia severity index; q, every; tid, three times daily; UAT, urinary antigen test; WBC, white blood cell; yr, year(s) /FiO2 Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. 5740 Executive Drive Suite 220 Baltimore, MD 21228 TEL: 410-869-3332 • FAX: 410-744-2150 For additional copies: orders@GuidelineCentral.com Copyright © 2010 All rights reserved , arterial oxygen pressure/

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