Summary of Infection Control Measures for the Prevention of Horizontal Transmission of Clostridium difficile
Strength of Hand Hygiene
Contact Precautions a. Glove use b. Gowns
Private Room or Cohorting
Environmental cleaning, disinfection, or use of disposables a. Replace electronic rectal thermometers with disposables b. Use of hypochlorite (1000-5000 ppm) for disinfection if CDI rates are increased
Strength of Recommendation and Quality of Evidence Category/Grade
Defintion
Strength of Recommendation A B
C
Quality of Evidence I
II III Abbreviations
CDI, Clostridium difficile infection; PCR, polymerase chain reaction; EIA, Enzyme Immuno Assay; GDH, glutamate dehydrogenase
Sources Cohen SH, Gerding DN, Johnson SB, Kelly CP, Loo VG, McDonald LC, Pepin J, Wilcox MH. Clinical Practice Guidelines for Clostridium Difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 2010;31(5):431-55.
Disclaimer
This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.
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Good evidence to support a recommendation for or against use. Moderate evidence to support a recommendation for or against use. Poor evidence to support a recommendation.
Evidence from > 1 properly randomized, controlled trial.
Evidence from > 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from > 1 center); from multiple time-series; or from dramatic results from uncontrolled experiments.
Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.
Recommendation A-II
A-I
B-III C-III
B-II B-II
