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Chronic Kidney Disease in HIV-Infected Patients

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Disclaimer is Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care practitioners, and providers at all levels. is Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Abbreviations ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; ACR, albumin-to-creatinine ratio; AER, albumin excretion rate; ART, antiretroviral therapy; ARV, antiretroviral; ATV, atazanavir; bid, twice daily; CKD, chronic kidney disease; CKD-EPI, Chronic Kidney Disease Epidemiolog y Collaboration; CrCl, creatinine clearance; CYP3A4, cytochrome P450 isoenzyme 3A4; ESRD, end-stage renal disease; FE phos , fractional excretion of phosphate; FE UA , fractional excretion of uric acid; GFR, glomerular filtration rate; HD, hemodialysis; HIV, human immunodeficiency virus; HIVAN, HIV-associated nephropathy; INSTI, integrase strand transfer inhibitor; LPV, lopinavir; min, minute; NNRTI, nonnucleoside reverse transcriptase inhibitor; NR, not reported; PCR, protein-to-creatinine ratio; P creat , plasma concentration of creatinine; PD, peritoneal dialysis; PER, protein excretion rate; PI, protease inhibitor; PO, by mouth; P phos , plasma concentration of phosphorus; P UA , plasma concentration of uric acid; qhs, every night at bedtime; RCT, randomized controlled trial; tid, 3 times daily; TmP/GFR, tubular maximum for phosphate corrected for glomerular filtration rate; U alb , urine concentration of albumin; uAPR, urine albumin-to-protein ratio; U creat , urine concentration of creatinine; U phos , urine concentration of phosphorus; U prot , urine concentration of protein; U UA , urine concentration of uric acid; WHO, World Health Organization Source Lucas GM, Ross MJ, Stock PG, et al. Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America. Clin Infect Dis. 2014 Sep 17. pii: ciu617. [Epub ahead of print] 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 For additional copies: Copyright © 2014 All rights reserved IDSACHR14113

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