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Atrial Fibrillation

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32 Management 5.2.1. Weight Loss in Individuals Who Are Overweight or Obese COR LOE Recommendation 1 B-R 1. In patients with AF who are overweight or obese (with BMI >27 kg/m 2 ), weight loss is recommended, with an ideal target of at least 10% weight loss to reduce AF symptoms, burden, recurrence, and progression to persistent AF. 5.2.2. Physical Fitness COR LOE Recommendation 1 B-R 1. In individuals with AF,* moderate to vigorous exercise training to a target of 210 minutes per week is recommended to reduce AF symptoms and burden, increase maintenance of sinus rhythm, increase functional capacity, and improve QOL. * In patients without AF related to excessive exercise training. 5.2.3. Smoking Cessation COR LOE Recommendation 1 B-NR 1. Patients with a history of AF who smoke cigarettes should be strongly advised to quit smoking and should receive guideline-directed management and therapy (GDMT) for tobacco cessation to mitigate increased risks of AF-related cardiovascular complications and other adverse outcomes. 5.2. Secondary Prevention: Management of Comorbidities and Risk Factors

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