AAAAI & ACAAI GUIDELINES Bundle (free trial)

Figure 1. Recurrent Angioedema – Diagnostic Algorithm Recurrent Angioedema ACE-I/ARB- associated AE Not likely HAE or acquired C1INH deficiency; exclude drug cause and consider idiopathic NO YES YES Is patient taking an ACE-I or ARB? NO Stop ACE-I/ ARB. Does AE resolve? LOW Consider HAE with normal C1INH NORMAL YES Measure C4 level Not HAE; consider idiopathic AE NORMAL Measure C1INH antigen NORMAL NO Is there a familial history of AE? LOW NORMAL Measure C1q antigen Type I HAE Type II HAE Measure C1INH function LOW Acquired C1INH deficiency AE & Urticaria AE Only LOW Diagnosis

• Cover
• Key Points
• Diagnosis
• Prevention
• Treatment
• Special Cases
• Evidence Grading
• Drug Table