106 Commerce Street, Suite 105
Lake Mary, FL 32746
TEL: 407.878.7606 • FAX: 407.878.7611
For additional copies: info@GuidelineCentral.com
Copyright © 2013 All rights reserved
Disclaimer
is resource is a practice tool for physicians based on an ASCO
®
practice guideline. e practice
guideline and this tool are not intended to substitute for the independent professional judgment of
the treating physician. Practice guidelines do not account for individual variation among patients
and may not reflect the most recent evidence. is tool does not recommend any particular product
or course of medical treatment. Use of the practice guideline and this resource is voluntary. e full
practice guideline and additional information are available at http://www.asco.org/guidelines. Copyright
© 2013 by American Society of Clinical Oncology
®
. All rights reserved.
Abbreviations
ALC, absolute lymphocyte count; AMC, absolute monocyte count; ANC, absolute neutrophil
count; ASCO, American Society of Clinical Oncolog y; CHOP, cyclophosphamide,
hydroxydaunorubicin (doxorubicin), vincristine (Oncovin
™
), prednisone; CNS, central nervous
system; CR, complete response; ECOG, Eastern Cooperative Oncolog y Group; FN, febrile
neutropenia; FNE, febrile neutropenic event; Hb, hemoglobin; Hct, hematocrit; hr, hour;
IDSA, Infectious Diseases Society of America; IFI, invasive fungal infections; IV, intravenous;
MASCC, Multinational Association for Supportive Care in Cancer; MDS, myelodysplastic
syndromes; NCI, National Cancer Institute; NHL, non-Hodgkin's lymphoma; OMAS, oral
mucositis assessment scale; PR, partial response; PS, performance status; ULN, upper limit of
normal; WBC, white blood cell
Source
Flowers CR, Seidenfeld J, Bow EJ, et al. Antimicrobial prophylaxis and outpatient management
of fever and neutropenia in adults treated for malignancy: American Society of Clinical
Oncolog y clinical practice guideline. J Clin Oncol. 2013 Jan 14. [Epub ahead of print].
ASCOFEV130702d
Table 6. ECOG Performance Status
a
Grade ECOG
0 Fully active, able to carry on all pre-disease performance without restriction
1 Restricted in physically strenuous activity but ambulatory and able to carry out work
of a light or sedentary nature, eg, light house work, office work
2 Ambulatory and capable of all self-care but unable to carry out any work activities.
Up and about more than 50% of waking hours
3 Capable of only limited self-care. Confined to bed or chair more than 50% of waking
hours
4 Completely disabled. Cannot carry on any self-care. Totally confined to bed or chair
5 Dead
a
Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative
Oncolog y Group. Am J Clin Oncol. 1982;5:649-655.
Acknowledgement: Eastern Cooperative Oncolog y Group, Robert Comis, MD, Group Chair.
