Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer

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12 Disclaimer is pocket guide is derived om recommendations in the American Society of Clinical Oncology Guideline. is resource is a practice tool based on ASCO ® practice guidelines and is not intended to substitute for the independent professional judgment of the treating physician. Practice guidelines do not account for individual variation among patients. is pocket guide does not purport to suggest any particular course of medical treatment. Use of the practice guidelines and this resource are voluntary. e practice guidelines and additional information are available at Copyright ©2019 by American Society of Clinical Oncology. All rights reserved. Source Key NS et al. Venous romboembolism Prophylaxis and Treatment in Patients with Cancer. J Clin Oncol. 2019 Aug 5:JCO1901461. doi: 10.1200/JCO.19.01461. [Epub ahead of print] 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at Copyright © 2019 All rights reserved ASCOVTE1972a ASCO believes that cancer clinical trials are vital to inform medical decisions and improve cancer care and that all patients should have the opportunity to participate. Additional information, which may include data supplements, slide sets, and other clinical tools and resources, is available at Abbreviations aPTT, activated partial thromboplastin time; bid, twice daily; CNS, central nervous system; d, day; DOAC, direct oral anticoagulants; GI, gastrointestinal; h, hour; INR, international normalized ratio; IV, intravenous; kg, kilogram; mg, milligram; pre-op, pre-operatively; PO, oral; post-op, post-operatively; q, every; qd, every day; U, unit; VTE, venous thromboembolism; wks, weeks Recommendation Grading Type Benefit/harm Evidence Quality Strength of Recommendation EB Evidence- based B Benefits outweigh harms H High Strong FC Formal consensus H Harms outweigh benefits I Intermediate Moderate IC Informal consensus B/H Relative balance of benefits and harms L Low Weak Ins Insufficient

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