ASCO GUIDELINES Bundle

Treatment for Brain Metastases

ASCO GUIDELINES App Bundle brought to you fcourtesy of Guideline Central. All of these titles are available for purchase on our website, GuidelineCentral.com. Enjoy!

Issue link: https://eguideline.guidelinecentral.com/i/1475506

Contents of this Issue

Navigation

Page 1 of 5

Key Points ➤ In the United States, it is estimated that between 8% and 10% of patients with cancer will develop brain metastases representing ~200,000 new patients with brain metastases every year. ➤ The most likely primary cancers to seed brain metastases are melanoma, lung adenocarcinoma, and those from lung, breast, melanoma, renal, kidney, esophagus, and, head and neck. ➤ This guideline was developed by a multi-disciplinary team of medical oncologists, neurosurgeons, neuro-oncologists and radiation oncologists, and it integrates the latest evidence supporting the use of surgery, radiation, and medical therapies for patients with CNS metastases. Treatment Recommendation 1.1 ➤ Surgery may be offered for patients with brain metastases, considering the following factors: • Patients with suspected brain metastases without a primary cancer diagnosis may benefit from surgery to attain a diagnosis and undergo tumor removal. • Patients with large tumors with mass effect likely benefit from surgery. Patients with multiple brain metastases and/or uncontrolled systemic disease are less likely to benefit from surgery unless the remaining disease is controllable via other measures. (Moderate recommendation; EB-mixed) Recommendation 1.2 ➤ Where surgery is considered, no recommendation regarding the method of resection (piecemeal vs. en bloc) can be made. (IC-L) Recommendation 1.3 ➤ No recommendation can be made for or against LITT. (IC-L)

Articles in this issue

Archives of this issue

view archives of ASCO GUIDELINES Bundle - Treatment for Brain Metastases