15
Strength of Recommendations
Grade Definition
Strong ere is high confidence that the recommendation reflects best practice.
is is based on:
• strong evidence for a true net effect (e.g., benefits exceed harms);
• consistent results, with no or minor exceptions;
• minor or no concerns about study quality; and/or
• the extent of panelists' agreement.
Other compelling considerations (discussed in the guideline's literature
review and analyses) may also warrant a strong recommendation.
Moderate
ere is moderate confidence that the recommendation reflects best
practice. is is based on:
• good evidence for a true net effect (e.g., benefits exceed harms);
• consistent results with minor and/or few exceptions;
• minor and/or few concerns about study quality; and/or
• the extent of panelists' agreement.
Other compelling considerations (discussed in the guideline's literature
review and analyses) may also warrant a moderate recommendation.
Weak ere is some confidence that the recommendation offers the best current
guidance for practice. is is based on:
• limited evidence for a true net effect (e.g., benefits exceed harms);
• consistent results, but with important exceptions;
• concerns about study quality; and/or
• the extent of panelists' agreement.
Other considerations (discussed in the guideline's literature review and
analyses) may also warrant a weak recommendation.
