2
Key Points
➤ Approximately 45% of incident colorectal cancers occurred in less-
developed regions around the world, representing 9–10% of cancers
in those regions. Fifty-two percent of deaths from colorectal cancer
occurred in these "less-developed" regions.
• Many regions do not have mass or even opportunistic screening, and even within
regions with mass screening subpopulations may not have access to screening.
➤ In recognition of the resource limitations in these regions and to
improve the quality of care where resources are limited, ASCO
has established a process for development of resource-stratified
guidelines, which includes mixed methods of evidence-based
guideline development, adaptation of the clinical practice guidelines
of other organizations, and formal expert consensus.