ATS GUIDELINES Bundle

106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2021 All rights reserved ATSFENO10213a Abbreviations CPG, clinical practice guideline; EtD, Evidence to Decision; FeNO, fractional exhaled nitric oxide; NO, nitric oxide Source Khatri SB et al. Use of Fractional Exhaled Nitric Oxide (FeNO) to Guide the Treatment of Asthma. An Official American oracic Society Clinical Practice Guideline. Am J Respir Crit Care. Nov 15 2021; 204(10): e97–e109. Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Table 1. Grading of Recommendations, Assessment, Development, and Evaluation (GRADE)-based Recommendations Strong Recommendation Conditional Recommendation For clinicians Most patients should receive the recommended course of action. Most patients should receive the recommended course of action. However, conversation with the patient regarding the uncertainty in the anticipated balance of effects is warranted. For patients Most patients in this situation would want the recommended intervention. e majority of individuals in this situation would want the suggested intervention. However, a conversation regarding alternative available management options may be warranted. For policy makers e recommendation can be adapted as policy in most situations including for the use as performance indicators. Policies are likely to vary between regions/ health systems, but should be based on adequate deliberation over alternative available management options. Certainty of Evidence Definition Very low e true effect is probably markedly different from the estimated effect. Low e true effect might be markedly different from the estimated effect. Moderate e authors believe that the true effect is probably close to the estimated effect. High e authors have a lot of confidence that the true effect is similar to the estimated effect.

• Cover