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Obesity Overview - OMA Obesity Algorithm 2023

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13 Body Weight Homeostasis   ➤ RMR has genetic variance, mainly via body mass-dependent energy expenditure (i.e., individuals of male gender, increased height, increased muscle, younger age and obesity typically have higher RMR). An increase in fat free mass may not only increase RMR, but may also increase hunger, which influences the nutritional aspect of energy balance. Beyond RMR, other common contributors to variances in energy expenditure include NEAT, physical exercise, and thermogenesis of food. Finally, metabolic rate (MR) can be affected by climate (hotter environment increases MR to cool the body; colder environment increases MR through non-shivering thermogenesis to warm the body). Energy Expenditure: Components Overall In individuals with moderate physical inactivity, components of total energy expenditure: • 70% resting MR • 20% physical activity • 10% diet-induced thermogenesis With the exception of individuals engaged in physical exercise outside typical study populations, the coefficient of variation in humans regarding energy expenditure a : • Resting MR = 10% • Physical exercise = 2% • Diet-induced thermogenesis = 20% b a NEAT also contributes to variances in energ y expenditure. b Whole foods generally generate higher diet-induced thermogenesis than ultra-processed food.

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