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Obesity Overview - OMA Obesity 2021

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2 Key Points   ➤ Multiple factors contribute to the development of obesity and its consequences. • Environment, genetics and epigenetic influences all influence the condition. • Environmental elements include cultural, life style, emotional conditions, medications, toxins, infections, hormonal imbalances and gut microbiota.   ➤ In 2017–2018, the prevalence of obesity was estimated to be ~42% in U.S. adults (≥20 years of age) and ~18.5% of youths (2–19 years of age).   ➤ According to a projection analysis in 2019, ~50% of U.S. adults will have obesity by 2030, with ~25% of adults having severe obesity (body mass index [BMI] ≥35 kg/m 2 ). Definition   ➤ "Obesity is defined as a chronic, progressive, relapsing, and treatable multi-factorial, neurobehavioral disease, wherein an increase in body fat promotes adipose tissue dysfunction and abnormal fat mass physical forces, resulting in adverse metabolic, biomechanical, and psychosocial health consequences." Classification of Obesity Body Mass Index (BMI) Body mass index (BMI) in kilograms per meters squared (kg/m 2 ) a Normal Weight 18.5–24.9 Overweight 25.0–29.9 Class I Obesity 30.0–34.9 Class II Obesity 35.0–39.9 Class III Obesity ≥40 Waist Circumference (WC) b Abdominal Obesity – Men ≥40 inches ≥102 centimeters Abdominal Obesity – Women ≥35 inches ≥88 centimeters a Different BMI cut-off points may be more appropriate based upon gender, race, ethnicity, and menopausal status. For example, among Asians, a BMI >23 kg/m2 may be a more appropriate cut- off point to define overweight and to screen for type 2 diabetes mellitus. Among postmenopausal women, BMI may underestimate percent body fat. b Different WC abdominal obesity cut-off points are appropriate for different races (i.e., ≥ 90 centimeters for Asian men and ≥ 80 centimeters for Asian women)

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