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Disclaimer
is pocket guide attempts to define principles of practice that should produce high-quality patient
care. It is applicable to specialists, primary care, and providers at all levels. is pocket guide
should not be considered exclusive of other methods of care reasonably directed at obtaining the same
results. e ultimate judgment concerning the propriety of any course of conduct must be made by
the clinician aer consideration of each individual patient situation. Neither IGC, the medical
associations, nor the authors endorse any product or service associated with the distributor of this
clinical reference tool.
NHFBLE19123b
Drugs
Agent Dose
a
Desmopressin ≥0.3 mcg/kg subcutaneously or else
intravenously in 30 mL normal saline over
30 minutes
Desmopressin nasal spray
"Stimate
®
"
1 spray in one nostril for individuals <50 kg
1 spray in each nostril for individuals >50 kg
Factor VIII ≥50 units/kg
Recombinant factor VIIa (rFVIIa) ≥90 mcg/kg
Factor IX 100–120 units/kg
Activated prothrombin complex concentrates
(FEIBA)
≥75–100 units/kg
a
Dose should produce a factor level of 80%–100%. Highest doses are for severe bleeding.
Abbreviations
CAT, computerized axial tomography; PT, prothrombin time; PTT, partial thromboplastin
time
Source
National Hemophilia Foundation. Guidelines for Emergency Department Management of
Individuals With Hemophilia and Other Bleeding Disorders. Available at: https://www.
hemophilia.org/sites/default/files/document/files/257.pdf.
