2
Key Points
➤ Nosebleed, also known as epistaxis, is a common problem that occurs
at some point in at least 60% of people in the United States.
• About 6% of people who experience nosebleeds will seek medical attention.
Table 1. Applying the Nosebleed CPG: Target Patient and
Practice Settings
Target Patient Exclusions
Practice Settings/
Encounter Type
• Age ≥3 years
• Nosebleed that is
severe, persistent,
recurrent, or affects
quality of life.
• Age <3 years
• Nasal or
nasopharyngeal tumor
• Vascular malformation
of the head and neck
• Diagnosed bleeding
disorder
• Recent facial trauma
• Recent sinus and/or
nasal surgery
• Outpatient office or
clinic
• Emergency department
• Hospital (wards,
radiolog y suites,
operating rooms)
• Phone call encounters
• Emails/texts
• Telemedicine
Diagnosis
Table 2. Risk Factors Associated with Nosebleed
Prior nasal or sinus surgery
Nasal or facial trauma
Nasal cannula oxygen use
Continuous positive airway pressure (CPAP) use
Intranasal medication or drug use
Use of medications which impair coagulation and/or platelet function
Personal or family history of bleeding disorder
Chronic kidney or liver disease
