Endocrine Society GUIDELINES Bundle (free trial)

Cushing's Syndrome Treatment

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Abbreviations ACC, adrenocortical carcinoma; ACTH, adrenocorticotropic hormone; ADX, adrenalectomy; BMAH, bilateral macronodular adrenal hyperplasia; BMD, bone mineral density; CBG, corticosteroid binding globulin; CD, Cushing's disease; CNS, central nervous system; CS, Cushing's syndrome; DDI, drug-drug interactions; EAS, ectopic ACTH secretion; ES, Endocrine Society; f T4, free thyroxine; GC, glucocorticoid; GH, growth hormone; GI, gastrointestinal; h, hours; HPA, hypothalamic-pituitary-adrenal; HRQOL, health-related quality of life; HT, hypertension; HU, Hounsfield units; ICU, intensive care unit; IPSS, inferior petrosal sinus sampling ; LFTs, liver function tests; QOL, quality of life; QTc, corrected QT interval; RT, radiation therapy; SST, somatostatin receptor; T4, thyroid hormone; TSS, transsphenoidal selective adenomectomy; UFC, urine free cortisol; WBC, white blood cell count Source Nieman LK, Biller BMK, Findling JW, et al. Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2015;100(8):2807-31. Grading System Strength of Recommendation 1 = strong 2 = less strong US = Ungraded best practice statement Quality of Evidence ⊕⊕⊕⊕ = high ⊕⊕⊕ = moderate ⊕⊕ = low ⊕ = very low 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2015 All rights reserved ESCUS15123 Disclaimer is Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. is Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.

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