Diagnosis
Adrenals
Congenital adrenal hyperplasia (select types)
Cushing syndrome
Addison disease (adrenal insufficiency)
Tumor (androgen-secreting )
Ovaries
Associated with high levels of gonadotropins
Gonadal agenesis or dysgenesis (in the setting of Turner syndrome/other)
Ovarian insufficiency
Autoimmune oophoritis
Irradiation or surgery
Not associated with high levels of gonadotropins
Polycystic ovary syndrome
Tumor (estrogen- or androgen-secreting )
Uterus (eugonadism)
Müllerian anomalies (obstructive outflow anomalies)
Asherman syndrome
Synechiae (integral to Asherman syndrome)
Pregnancy
Infectious (e.g., tuberculous endometritis)
Agenesis (uterine or cervical)
Vagina (eugonadism)
Agenesis
Transverse septum
Hymen (eugonadism)
Imperforate
Table 1. Potential Etiologies of Amenorrhea (cont'd)
