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Hypothalamic Pituitary and Growth Disorders

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106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved ESHYP1883 Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation.Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Source Sklar CA et al. Hypothalamic-Pituitary and Growth Disorders in Survivors of Childhood Cancer: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab, July 2018, 103(8):1–24. Abbreviations ACTH, adrenocorticotropic hormone; ACTHD, adrenocorticotropic hormone deficiency; AH, adult height; CNS, central nervous system; CPP, central precocious puberty; CRT, cranial radiation therapy; CSI, craniospinal irradiation; f T4, free T4; GHD, growth hormone deficiency; GHT, growth hormone treatment; GnRHa, gonadotropin-releasing hormone agonist; Gy, Gray; HP, hypothalamic-pituitary; ITT, insulin tolerance test; LH/FSHD, luteinizing hormone/follicle-stimulating hormone deficiency; RT, radiation treatment; SCFE, slipped capital femoral epiphysis; TBI, total body irradiation; T2DM, type 2 diabetes mellitus; TKI, tyrosine kinase inhibitor; TSH, thyroid-stimulating hormone; TSHD, thyroid-stimulating hormone deficiency Grading System Strength of Recommendation 1 = strong 2 = conditional UGPS = ungraded good practice statement Quality of Evidence ⊕⊕⊕⊕ = high ⊕⊕⊕ = moderate ⊕⊕ = low ⊕ = very low

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