Table 1. Normative Values
Wakefulness Sleep Desaturation nadir
Mean
(±SD)
Median
(range)
Mean
(±SD)
Median
(range)
Mean
(±SD)
Median
(range)
Children <1 year old
97.8%
(±1.4%)
98.7%
(97.9% to
99.8%)
96.3%
(±1.3%)
Not reported
86% (±1.5%) 85.5% (83%
to 88%)
Children ≥1 year old
97.6%
(±0.7%)
97.5% (97%
to 98%)
97.8%
(±0.7%)
Not reported 94.6%
(±3.1%)
93% (91% to
94%)
Treatment
Cystic Fibrosis
➤ For patients with cystic fibrosis complicated by severe chronic
hypoxemia, the ATS recommends that home oxygen therapy be
prescribed (strong recommendation, very low quality evidence).
➤ For patients with cystic fibrosis who have both mild chronic hypoxemia
and dyspnea on exertion, the ATS suggests that home oxygen therapy be
prescribed (conditional recommendation, very low quality evidence).
Bronchopulmonary Dysplasia
➤ For patients with bronchopulmonary dysplasia complicated by chronic
hypoxemia, the ATS recommends that home oxygen therapy be
prescribed (strong recommendation, very low quality evidence).
Sleep-Disordered Breathing
➤ For patients with sleep-disordered breathing complicated by severe
nocturnal hypoxemia who cannot tolerate positive airway pressure
therapy or are awaiting surgical treatment of sleep-disordered
breathing, the ATS suggests that home oxygen therapy be prescribed
(conditional recommendation, very low quality evidence).
Sickle Cell Disease
➤ For patients with sickle cell disease complicated by severe chronic
hypoxemia, the ATS suggests that home oxygen therapy be prescribed
(conditional recommendation, very low quality evidence).
Diagnosis
