ATS GUIDELINES Bundle

Home Oxygen Therapy for Children

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Table 1. Normative Values Wakefulness Sleep Desaturation nadir Mean (±SD) Median (range) Mean (±SD) Median (range) Mean (±SD) Median (range) Children <1 year old 97.8% (±1.4%) 98.7% (97.9% to 99.8%) 96.3% (±1.3%) Not reported 86% (±1.5%) 85.5% (83% to 88%) Children ≥1 year old 97.6% (±0.7%) 97.5% (97% to 98%) 97.8% (±0.7%) Not reported 94.6% (±3.1%) 93% (91% to 94%) Treatment Cystic Fibrosis ➤ For patients with cystic fibrosis complicated by severe chronic hypoxemia, the ATS recommends that home oxygen therapy be prescribed (strong recommendation, very low quality evidence). ➤ For patients with cystic fibrosis who have both mild chronic hypoxemia and dyspnea on exertion, the ATS suggests that home oxygen therapy be prescribed (conditional recommendation, very low quality evidence). Bronchopulmonary Dysplasia ➤ For patients with bronchopulmonary dysplasia complicated by chronic hypoxemia, the ATS recommends that home oxygen therapy be prescribed (strong recommendation, very low quality evidence). Sleep-Disordered Breathing ➤ For patients with sleep-disordered breathing complicated by severe nocturnal hypoxemia who cannot tolerate positive airway pressure therapy or are awaiting surgical treatment of sleep-disordered breathing, the ATS suggests that home oxygen therapy be prescribed (conditional recommendation, very low quality evidence). Sickle Cell Disease ➤ For patients with sickle cell disease complicated by severe chronic hypoxemia, the ATS suggests that home oxygen therapy be prescribed (conditional recommendation, very low quality evidence). Diagnosis

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