Antimicrobial Prophylaxis in Surgery (free version)

ASHP Surgical Prophylaxis Guidelines

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Recommendation Grading Strength of Evidence and Grading Recommendation Level I Evidence from large, well-conducted randomized, controlled clinical trials or a meta-analysis Level II Evidence from small, well-conducted randomized, controlled clinical trials Level III Evidence from well-conducted cohort studies Level IV Evidence from well-conducted case���control studies Level V Evidence from uncontrolled studies that were not well conducted Level VI Conflicting evidence that tends to favor the recommendation Level VII Expert opinion or data extrapolated from evidence for general principles and/or other procedures Category A Levels I-III Category B Levels IV-VI Category C Level VII Abbreviations hrs, hours; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillinsensitive S. aureus; NHSN, National Healthcare Safety Network; SSI, surgical site infection Source Bratzler DW, Dellinger EP, Olsen KM, Perl T, Auwaerter PG, Bolon MK, Fish DN, Napolitano LM, Sawyer RG, Slain D, Steinberg JP, Weinstein RA. Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. Am J Health Syst Pharm. 2013 ��� Feb 1;70(3):195-283. Disclaimer The recommendations in these guidelines may not be appropriate for use in all clinical situations. Decisions to follow these recommendations must be based on the judgment of the clinician and consideration of individual patient circumstances and available resources. These guidelines reflect current knowledge (at the time of publication) of antimicrobial prophylaxis in surgery. Given the dynamic nature of scientific information and technology, periodic review, updating, and revisions are to be expected. This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. SUR01132l 5740 Executive Drive��� Suite 218 Baltimore, MD 21228��� TEL: 410-869-3332��� ������ FAX: 410-744-2150��� For additional copies: orders@GuidelineCentral.com Copyright �� 2013 All rights reserved

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